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GLP-1 receptor agonistFDA-approved December 2017 (Ozempic) · June 2021 (Wegovy)Rx · Subcutaneous injection (weekly) · oral tablet (daily) · Once weekly (injectable)

Semaglutide
(Ozempic, Wegovy, Rybelsus) in Chapel Hill, NC

Dr. Fahad Akhtar, M.D.
Medically reviewed by Dr. Fahad Akhtar, M.D.
Physician at g1v.me, an affiliated practice

Physicians near Chapel Hill, NC from the federal NPI registry. Ask each office whether it prescribes Ozempic, Wegovy, or Rybelsus.[9]

  • Ozempic: FDA-approved for type 2 diabetes.
  • Wegovy: FDA-approved for chronic weight management.
  • Rybelsus: FDA-approved for type 2 diabetes.
city providers
40
as of today

Same molecule (semaglutide): Ozempic in Chapel Hill, Wegovy in Chapel Hill

Other GLP-1 medicines: Tirzepatide in Chapel Hill, Mounjaro in Chapel Hill, Zepbound in Chapel Hill

§ 02Provider directory: North Carolina
40 of 40 shown

Find a physician in Chapel Hill.

Every entry comes from the federal NPI registry. Ask each office what it prescribes. We do not accept payment for placement.

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Provider
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Semaglutide by North Carolina town, physicians per town
§ 03Getting Semaglutide in Chapel Hill
40 providers · Chapel Hill, NC

How to get Semaglutide in Chapel Hill.

40 GLP-1 prescribers and 7 local resource types are on record for Chapel Hill, plus 3 nearby towns in the directory.

Physicians in Chapel Hill
40 physicians
40 physicians from the federal NPI registry in Chapel Hill, most listed as Internal Medicine, Endocrinology, Diabetes & Metabolism (14), Family Medicine (14) and Internal Medicine (8). A licensed clinician who evaluates you decides whether an FDA-approved GLP-1 fits. Telehealth rules vary by state. The nearest towns on record are Durham (39 providers), Cary (29 providers) and Apex (28 providers).
Around the prescription in Chapel Hill
7 listed nearby
181 dietitians, 17 nutritionists, 6 gyms, 6 fitness clubs, 6 trainers, 6 physiotherapists and 6 places to move are on record near Chapel Hill.
Medicaid (weight loss)
Covered
As of April 2026, North Carolina Medicaid covers GLP-1s for weight loss, usually with prior authorization and BMI criteria, on top of the standard diabetes coverage. Employer and private plans vary; coverage is a plan-design choice, not a state rule.

Medicaid status above is for weight-loss use and was compiled April 2026 from KFF and public Medicaid trackers; only 13 states cover it and several are mid-change, so confirm North Carolina’s current Medicaid and plan rules before booking. GLPHelper provides information and provider matching, not medical or coverage advice.

§ 04Medication factsheet
cited · last review 2026.05.19

The molecule in Ozempic, Rybelsus, and Wegovy. The brands differ in approved use and maximum dose.

Semaglutide is a once-weekly GLP-1 receptor agonist sold under three brand names by Novo Nordisk: Ozempic and Rybelsus for type 2 diabetes, and Wegovy for chronic weight management. It mimics a gut hormone that signals satiety to the brain and slows gastric emptying. The injectable forms share the same molecule; only the approved indication and maximum dose differ.[2][3]

In the STEP-1 obesity trial, adults without diabetes taking Wegovy (semaglutide 2.4 mg) lost a mean of 14.9% of body weight at 68 weeks versus 2.4% with placebo. In the SELECT trial, semaglutide 2.4 mg reduced major adverse cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease but without diabetes.[1]

Bar chart of Semaglutide dose strengths on the FDA label: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, 2.4 mg, 7.2 mg (Wegovy HD)
Semaglutide comes in 6 strengths: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, 2.4 mg, 7.2 mg (Wegovy HD). The chart shows what the label lists. A prescriber sets the dose.[1]
At a glanceMultiple (brand-specific)
Active ingredient
semaglutide
Drug class
GLP-1 receptor agonist
Manufacturer
Novo Nordisk
FDA approved
December 2017 (Ozempic) · June 2021 (Wegovy)
Approved use
Type 2 diabetes (Ozempic/Rybelsus) · chronic weight management (Wegovy)
Off-label use
Use outside the approved brand/indication is off-label
Administration
Subcutaneous injection (weekly) · oral tablet (daily) · Once weekly (injectable)
Available doses
0.25 mg · 0.5 mg · 1 mg · 1.7 mg · 2.4 mg · 7.2 mg (Wegovy HD)
Half-life
≈ 7 days
Pregnancy
Discontinue ≥ 2 months before a planned pregnancy

Community health · CDC

Weight & metabolic health in Chapel Hill

Chapel Hill, North Carolina has a population of 61,960 people. The adult obesity rate in Chapel Hill is an age-adjusted estimate of 28.8%, 5.7 percentage points below the North Carolina state rate of 34.5%. Diagnosed diabetes reaches 8.9% of adults in Chapel Hill. Inactivity, meaning no leisure-time physical activity reported in the past month, affects 18.6% of adults in Chapel Hill.

of Chapel Hill adults have obesity
28.8%
diagnosed diabetes
8.9%
no regular physical activity
18.6%

Age-adjusted estimates for Chapel Hill, community figures, not individual risk. CDC PLACES, 2025 release.

Estimate your weight losswhat to expect week by week
§ 05Support around Semaglutide in Chapel Hill
6 nutritionists

The prescription is one part. Here is the rest, in Chapel Hill.

Trials of semaglutide paired the drug with diet counseling and regular activity. Every name below is a real listing near Chapel Hill, NC, ordered as the registry lists them, never by who pays us.

Nutritionists

A nutritionist helps you get enough protein and fiber while the medication cuts your appetite. Call to ask what they cover.

Cynthia Bartlett
NUTRITIONIST
Nutritionist
101 Manning Dr
Call 984-974-5762NPI 1942870761
Kathryn Bridgens
NUTRITIONIST
Nutritionist
101 Manning Dr
Call 984-974-5300NPI 1053957019
Devin Buss, MPH
NUTRITIONIST
Nutritionist
6633 Fairview Rd
Call 704-366-1264NPI 1326662511
Emily Greene, RD, LDN
NUTRITIONIST
Nutritionist
1100 E Wendover Ave
Call 336-641-3214NPI 1740300227
Renee Kemske, RD,LDN
NUTRITIONIST
Nutritionist
2501 Homestead Rd
Call 919-968-2022NPI 1922175140
Lamia Nasrallah, PLDN
NUTRITIONIST
Nutritionist
101 Manning Dr
Call 984-974-1183NPI 1730503046

Gyms near you

A gym gives you the regular movement that keeps muscle while the weight comes off.

Planet Fitness
GYM
4.3 on Google · 814 reviews
257 S Elliott Rd
Website
CrossFit Local | Voted #1 Chapel Hill CrossFit
GYM
5.0 on Google · 228 reviews
7401 Rex Rd #106
Website
F45 Training East Chapel Hill NC
GYM
5.0 on Google · 211 reviews
1728 Fordham Blvd #113
Website
Gold's Gym Chapel Hill
GYM
4.0 on Google · 209 reviews
6118 Farrington Rd
Website
Orangetheory Fitness
GYM
4.8 on Google · 204 reviews
104 Meadowmont Village Cir
Website
Onelife Fitness - Durham - Chapel Hill
GYM
4.9 on Google · 129 reviews
3420 SW Durham Dr
Website
§ 06Clinical evidence
STEP 1 to 4 + SELECT (N = 17,604)

What the trials actually showed.

We summarize the STEP weight-management program, the SUSTAIN diabetes program, and the SELECT cardiovascular outcomes trial. Figures are means at each trial's primary endpoint.

STEP-1 randomized 1,961 adults with overweight or obesity (without diabetes) to semaglutide 2.4 mg or placebo for 68 weeks. Mean weight change was −14.9% with semaglutide versus −2.4% with placebo; 86% of treated patients lost ≥5% of body weight.[2]
STEP / SELECT endpoint table2.4 mg / 68 wk
Mean weight change (Wegovy 2.4 mg)
−14.9%
STEP-1, 68 wk vs −2.4% placebo[2]
Patients losing ≥5% body weight
86%
STEP-1, 2.4 mg[2]
Major adverse cardiac events
−20%
SELECT, HR 0.80[3]
HbA1c reduction (T2D)
−1.4 to −1.8%
SUSTAIN program[4]
Effect size varies with baseline characteristics and adherence. Individual response may differ materially.
average semaglutide weight loss →mapped to your starting weight
§ 07Safety & adverse events
from FDA label, sect. 6.1

Most Semaglutide side effects are stomach and gut effects.

In Wegovy's weight trials at 2.4 mg, the most common side effects were nausea (44%), diarrhea (30%), vomiting (24%), and constipation (24%). Ozempic's lower diabetes doses showed lower rates.[1] Serious events were rare but include pancreatitis, gallbladder disease, and an FDA boxed warning regarding thyroid C-cell tumors based on rodent data.[1]

Boxed warning. Boxed warning: risk of thyroid C-cell tumors. Contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN-2).
Effect
Frequency
Severity
Note
Nausea
15.8 to 44%
mild
Lowest on Ozempic 0.5 mg, highest on Wegovy 2.4 mg
Diarrhea
8.5 to 30%
mild
More frequent during dose escalation
Vomiting
5 to 24%
mild
Reduced by slower titration
Constipation
3.1 to 24%
mild
Abdominal pain
5.7 to 20%
moderate
Pancreatitis
<0.3%
serious
Discontinue if acute pancreatitis is suspected
Gallbladder disease
0.4 to 2.5%
serious
Gallstones. Lowest on Ozempic 1 mg, highest on Wegovy tablets. Risk rises with rapid weight loss
Thyroid C-cell tumors
rodent data
boxed warning
Contraindicated with MTC or MEN-2 history
§ 08Cost & coverage, published, not gated
USD · monthly

What Semaglutide costs, by how you pay.

The price you pay depends on your insurance plan, your diagnosis, and how you buy. Manufacturer self-pay programs cost far less than pharmacy retail. Here are the ranges.

Data sources: GoodRx national retail survey[6], CMS Part D formulary files[5], Novo Nordisk self-pay and savings pages.

Self-pay and savings card prices checked . Retail averages from May 2026.

Semaglutide monthly cost by how you pay
Wegovy, pharmacy retail$1,610 to $1,788per monthBrand-name retail average, May 2026[6]
Wegovy, NovoCare self-pay$349 to $399per monthPen $349, Wegovy HD 7.2 mg $399. Pill $149 to $299
Ozempic, pharmacy retail$1,476per monthBrand-name retail average, May 2026[6]
Commercial insurance (T2D)$25 to $250per month copayUsually covered for diabetes with prior authorization
Commercial insurance (weight)Often deniedWegovy is on-label but frequently requires PA and is denied
Medicare Part D$0 to $100per monthType 2 diabetes covered. Wegovy for weight management is $50 a month through the Medicare GLP-1 Bridge, Jul 2026 to Dec 2027[5]
Manufacturer savings cardas low as $25per monthOzempic and Wegovy cards, commercial insurance only, up to $100 a month in savings
Find Semaglutide providers in Chapel Hill

Physicians from the federal NPI registry. Ask each office whether it prescribes Semaglutide.

Semaglutide in other states

Physicians from the federal NPI registry in the states we cover. Ask each office whether it prescribes Semaglutide.

Related GLP-1 research
§ 09Frequently asked: Semaglutide in North Carolina

The questions people ask before they book.

Answers reviewed by the glp·helper Medical Team. Citations link to primary sources, never marketing copy.

Semaglutide is the active ingredient in three Novo Nordisk brands: Ozempic, Wegovy, and Rybelsus. No generic semaglutide is FDA-approved in the US. Ozempic and Rybelsus are approved for type 2 diabetes; Wegovy is approved for chronic weight management at a higher maximum dose (7.2 mg/week, Wegovy HD). Insurers treat the brands as separate drugs.[1]