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Ozempic, Wegovy and the rest of the class — facts cited to FDA labels and clinical trials. Brand vs generic, dose vs dose.
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Trained exclusively on FDA labels, peer-reviewed literature, and CMS coverage policy. Inline citations on every claim.
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Medication deep-dives, mechanism explainers, and breakdowns of new trial data. Plain language, full citations.
One place for the whole GLP-1 landscape: every major medication — Ozempic, Wegovy, Mounjaro, Zepbound, and the semaglutide and tirzepatide generics — with side-by-side comparisons, NPI-verified providers in all 50 states, and a weight-loss calculator, every figure cited to FDA labels and peer-reviewed trials.
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Mechanism, dosing, cost and side effects — cited to FDA labels.
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Hover any chip — like the one beside this claim[2]— and you'll see the original FDA label, peer-reviewed paper, or CMS policy document. We don't paraphrase marketing materials and we don't link out to other SEO content. Just the primary sources.
Q.01How much weight can you lose on a GLP-1 medication?
In the pivotal trials, semaglutide (Wegovy) averaged about 15% of body weight lost over 68 weeks and tirzepatide (Zepbound) about 21% over 72 weeks. Real-world results vary with dose, starting weight, and how long you stay on treatment.
Estimate your own resultsQ.02Which GLP-1 is best for weight loss?
In head-to-head trials, tirzepatide (Mounjaro and Zepbound) produced larger average weight loss than semaglutide (Ozempic and Wegovy). The best choice still depends on your goals, insurance coverage, and how you tolerate each one.
Compare GLP-1 medications side by sideQ.03How much does Ozempic or Wegovy cost without insurance?
Brand list prices are high, but manufacturer self-pay programs have cut cash prices — Wegovy's NovoCare self-pay runs around $349 per month, for example. What you actually pay depends heavily on your insurance plan.
See Ozempic cost and coverageQ.04Do you need a prescription for GLP-1 medications?
Yes. Ozempic, Wegovy, Mounjaro, and Zepbound are prescription-only and require evaluation by a licensed clinician, in person or by telehealth.
Find a GLP-1 provider near youQ.05Is there a GLP-1 pill instead of an injection?
Oral semaglutide (Rybelsus) is FDA-approved, and oral or sublingual compounded versions are marketed, though the evidence and regulation behind them vary. The injectable versions remain the most studied for weight loss.
Do oral GLP-1 pills work?Q.06What are the most common GLP-1 side effects?
Nausea, constipation, diarrhea, and reduced appetite are the most common. They're usually strongest during dose increases and ease over time as your body adjusts.
See the full side-effect timeline