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GLP-1 receptor agonistFDA-approved December 2017 (Ozempic) · June 2021 (Wegovy)Rx · Subcutaneous injection (weekly) · oral tablet (Rybelsus, daily) · Once weekly (injectable)

Semaglutide® providers &
prescriptions in Wilmington, NC

Verified Semaglutide providers in Wilmington, NC. Checked against the NPI registry, never ranked by who pays us.[7]

city providers
33
as of today
§ 02Provider directory: North Carolina
33 of 33 shown

Find a Semaglutide provider in North Carolina.

Every entry is checked against the federal NPI registry. We do not accept payment for placement.

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§ 03Getting Semaglutide in Wilmington
33 providers · Wilmington, NC

How to get Semaglutide in Wilmington.

33 GLP-1 prescribers and 7 local resource types are on record for Wilmington, plus 3 nearby towns in the directory.

Prescribers in Wilmington
33 prescribers
33 GLP-1 prescribers in Wilmington, most listed as Family Medicine (14), Internal Medicine, Endocrinology, Diabetes & Metabolism (12) and Internal Medicine (7). Any North Carolina-licensed physician, nurse practitioner, or PA can prescribe Semaglutide, over video or in person. The nearest towns on record are Jacksonville (24 providers), New Bern (27 providers) and Goldsboro (27 providers).
Around the prescription in Wilmington
7 listed nearby
112 dietitians, 8 nutritionists, 6 gyms, 6 fitness clubs, 6 trainers, 6 physiotherapists and 6 places to move are on record near Wilmington.
Medicaid (weight loss)
Covered
As of April 2026, North Carolina Medicaid covers GLP-1s for weight loss, usually with prior authorization and BMI criteria, on top of the standard diabetes coverage. Employer and private plans vary; coverage is a plan-design choice, not a state rule.

Medicaid status above is for weight-loss use and was compiled April 2026 from KFF and public Medicaid trackers; only 13 states cover it and several are mid-change, so confirm North Carolina’s current Medicaid and plan rules before booking. GLPHelper provides information and provider matching, not medical or coverage advice.

§ 04Medication factsheet
cited · last review 2026.05.19

The molecule in Ozempic, Rybelsus, and Wegovy. The brands differ in approved use and maximum dose.

Semaglutide is a once-weekly GLP-1 receptor agonist sold under three brand names by Novo Nordisk: Ozempic and Rybelsus for type 2 diabetes, and Wegovy for chronic weight management. It mimics a gut hormone that signals satiety to the brain and slows gastric emptying. The injectable forms share the same molecule; only the approved indication and maximum dose differ.[2][3]

In the STEP-1 obesity trial, adults without diabetes taking Wegovy (semaglutide 2.4 mg) lost a mean of 14.9% of body weight at 68 weeks versus 2.4% with placebo. In the SELECT trial, semaglutide 2.4 mg reduced major adverse cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease but without diabetes.[1]

At a glanceMultiple (brand-specific)
Generic name
semaglutide
Drug class
GLP-1 receptor agonist
Manufacturer
Novo Nordisk
FDA approved
December 2017 (Ozempic) · June 2021 (Wegovy)
Approved use
Type 2 diabetes (Ozempic/Rybelsus) · chronic weight management (Wegovy)
Off-label use
Use outside the approved brand/indication is off-label
Administration
Subcutaneous injection (weekly) · oral tablet (Rybelsus, daily) · Once weekly (injectable)
Available doses
0.25 mg · 0.5 mg · 1 mg · 1.7 mg · 2.4 mg
Half-life
≈ 7 days
Pregnancy
Discontinue ≥ 2 months before a planned pregnancy

Community health · CDC

Weight & metabolic health in Wilmington

Wilmington, North Carolina has a population of 115,451 people. The adult obesity rate in Wilmington is an age-adjusted estimate of 33.2%, 1.3 percentage points below the North Carolina state rate of 34.5%. Diagnosed diabetes reaches 10.1% of adults in Wilmington. Inactivity, meaning no leisure-time physical activity reported in the past month, affects 22.1% of adults in Wilmington.

of Wilmington adults have obesity
33.2%
diagnosed diabetes
10.1%
no regular physical activity
22.1%

Age-adjusted estimates for Wilmington, community figures, not individual risk. CDC PLACES, 2025 release.

Estimate your weight lossGLP-1s and hair loss
§ 05Support around Semaglutide in Wilmington
6 gyms

The prescription is one part. Here is the rest, in Wilmington.

Trials of semaglutide paired the drug with diet counseling and regular activity. Every name below is a real listing near Wilmington, NC, ordered as the registry lists them, never by who pays us.

Gyms near you

A gym gives you the regular movement that keeps muscle while the weight comes off.

Planet Fitness
GYM
4.6 on Google · 1310 reviews
68A S Kerr Ave
Website
Crunch Fitness - Wilmington
GYM
4.8 on Google · 988 reviews
356 College Rd
Website
Fit4life Health Clubs - Wilmington Shipyard Blvd
GYM
4.5 on Google · 625 reviews
4310 Shipyard Blvd #104
Website
Unleashed Fitness
GYM
5.0 on Google · 479 reviews
1108 Princess St
Website
Fit4life Health Clubs - Wilmington N. College Rd
GYM
4.6 on Google · 416 reviews
2307 N College Rd
Website
Lakeside Fitness Wilmington
GYM
4.9 on Google · 237 reviews
11 S Kerr Ave
Website

Fitness clubs and recreation centers

Fitness clubs and recreation centers run classes and pools, an easier start than a weight room.

O2 Fitness
FITNESS
4.8 on Google · 1658 reviews
200 Racine Dr
Website
Planet Fitness
GYM
4.6 on Google · 1310 reviews
68A S Kerr Ave
Website
Crunch Fitness - Wilmington
GYM
4.8 on Google · 988 reviews
356 College Rd
Website
Fit4life Health Clubs - Wilmington Shipyard Blvd
GYM
4.5 on Google · 625 reviews
4310 Shipyard Blvd #104
Website
Fit4life Health Clubs - Wilmington N. College Rd
GYM
4.6 on Google · 416 reviews
2307 N College Rd
Website
NeuStrength
TRAINING
5.0 on Google · 301 reviews
5751 Oleander Dr #8
Website
§ 06Clinical evidence
STEP 1 to 4 + SELECT (N = 17,604)

What the trials actually showed.

We summarize the STEP weight-management program, the SUSTAIN diabetes program, and the SELECT cardiovascular outcomes trial. Figures are means at each trial's primary endpoint.

STEP-1 randomized 1,961 adults with overweight or obesity (without diabetes) to semaglutide 2.4 mg or placebo for 68 weeks. Mean weight change was −14.9% with semaglutide versus −2.4% with placebo; 86% of treated patients lost ≥5% of body weight.[2]
STEP / SELECT endpoint table2.4 mg / 68 wk
Mean weight change (Wegovy 2.4 mg)
−14.9%
STEP-1, 68 wk vs −2.4% placebo[2]
Patients losing ≥5% body weight
86%
STEP-1, 2.4 mg[2]
Major adverse cardiac events
−20%
SELECT, HR 0.80[3]
HbA1c reduction (T2D)
−1.4 to −1.8%
SUSTAIN program[4]
Effect size varies with baseline characteristics and adherence. Individual response may differ materially.
average semaglutide weight loss →mapped to your starting weight
§ 07Safety & adverse events
from FDA label, sect. 6.1

Most side effects are gastrointestinal and resolve within weeks.

The most common adverse events in STEP trials were nausea (44%), diarrhea (30%), and vomiting (24%), more frequent at the 2.4 mg dose than at Ozempic doses, but typically transient.[1] Serious events were rare but include pancreatitis, gallbladder disease, and an FDA boxed warning regarding thyroid C-cell tumors based on rodent data.[8]

Boxed warning. Boxed warning: risk of thyroid C-cell tumors. Contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN-2).
Effect
Frequency
Severity
Note
Nausea
20 to 44%
mild
Most common; dose-dependent, usually eases after titration
Diarrhea
20 to 30%
mild
More frequent during dose escalation
Vomiting
16 to 24%
mild
Reduced by slower titration
Constipation
20 to 24%
mild
Abdominal pain
10%
moderate
Pancreatitis
<0.3%
serious
Discontinue if acute pancreatitis is suspected
Gallbladder disease
1.6 to 2.6%
serious
Cholelithiasis risk rises with rapid weight loss
Thyroid C-cell tumors
rodent data
boxed warning
Contraindicated with MTC or MEN-2 history
§ 08Cost & coverage, published, not gated
USD · monthly

Most directories hide the price. We don't.

Cash prices vary roughly 50× between the brand-name retail rate and a manufacturer savings card. The number you actually pay depends on your insurance plan, your diagnosis code, and which pharmacy fills the script. Here are the ranges, plainly.

Data sources: GoodRx national retail survey[6], CMS Part D formulary files[5], Novo Nordisk patient access program.

Cash, Wegovy (no insurance)
$1,300 to $1,400
per month
Brand-name retail average[6]
Cash, Ozempic (no insurance)
$950 to $1,150
per month
Brand-name retail average[6]
Commercial insurance (T2D)
$25 to $250
per month copay
Usually covered for diabetes with prior authorization
Commercial insurance (weight)
Often denied
Wegovy is on-label but frequently requires PA and is denied
Medicare Part D
$0 to $100
per month
T2D covered; weight-loss indication not covered by law[5]
Manufacturer savings card
as low as $0 to $25
per month
Commercial insurance only; eligibility limits apply
Updated weekly · last fetch 2026-05-18 04:00 UTCCost methodology →
Find Semaglutide providers in North Carolina

NPI-verified Semaglutide (semaglutide) prescribers and clinics, never ranked by who pays us.

Semaglutide in other states

Find NPI-verified Semaglutide (semaglutide) doctors, clinics, and pharmacies in the states we cover, never ranked by who pays us.

Related GLP-1 research
§ 09Frequently asked: Semaglutide in North Carolina

The questions people ask before they book.

Answers reviewed by the GLPHelper Medical Team. Citations link to primary sources, never marketing copy.

Yes. Semaglutide is the active molecule in all three Novo Nordisk products. Ozempic and Rybelsus are approved for type 2 diabetes; Wegovy is approved for chronic weight management at a higher maximum dose (2.4 mg/week). Insurers treat the brands as separate drugs.[1]