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GLP-1 receptor agonistFDA-approved December 2017 (Ozempic) · June 2021 (Wegovy)Rx · Subcutaneous injection (weekly) · oral tablet (daily) · Once weekly (injectable)

Semaglutide
(Ozempic, Wegovy, Rybelsus) in Costa Mesa, CA

Dr. Fahad Akhtar, M.D.
Medically reviewed by Dr. Fahad Akhtar, M.D.
Physician at g1v.me, an affiliated practice

Physicians near Costa Mesa, CA from the federal NPI registry. Ask each office whether it prescribes Ozempic, Wegovy, or Rybelsus.[9]

  • Ozempic: FDA-approved for type 2 diabetes.
  • Wegovy: FDA-approved for chronic weight management.
  • Rybelsus: FDA-approved for type 2 diabetes.
city providers
31
as of today

Same molecule (semaglutide): Ozempic in Costa Mesa, Wegovy in Costa Mesa

Other GLP-1 medicines: Tirzepatide in Costa Mesa, Mounjaro in Costa Mesa, Zepbound in Costa Mesa

§ 02Provider directory: California
31 of 31 shown

Find a physician in Costa Mesa.

Every entry comes from the federal NPI registry. Ask each office what it prescribes. We do not accept payment for placement.

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Semaglutide by California town, physicians per town
§ 03Getting Semaglutide in Costa Mesa
31 providers · Costa Mesa, CA

How to get Semaglutide in Costa Mesa.

31 GLP-1 prescribers and 7 local resource types are on record for Costa Mesa, plus 3 nearby towns in the directory.

Physicians in Costa Mesa
31 physicians
31 physicians from the federal NPI registry in Costa Mesa, most listed as Family Medicine (14), Internal Medicine (13) and Internal Medicine, Endocrinology, Diabetes & Metabolism (2). A licensed clinician who evaluates you decides whether an FDA-approved GLP-1 fits. Telehealth rules vary by state. The nearest towns on record are Fountain Valley (32 providers), Newport Beach (40 providers) and Santa Ana (29 providers).
Around the prescription in Costa Mesa
7 listed nearby
27 dietitians, 5 nutritionists, 6 gyms, 6 fitness clubs, 6 trainers, 6 physiotherapists and 6 places to move are on record near Costa Mesa.
Medicaid (weight loss)
Diabetes only
As of April 2026, California Medicaid covers GLP-1s for diabetes but not for weight loss. Employer and private plans can still cover them; that is a plan-design choice, not a state rule.

Medicaid status above is for weight-loss use and was compiled April 2026 from KFF and public Medicaid trackers; only 13 states cover it and several are mid-change, so confirm California’s current Medicaid and plan rules before booking. GLPHelper provides information and provider matching, not medical or coverage advice.

§ 04Medication factsheet
cited · last review 2026.05.19

The molecule in Ozempic, Rybelsus, and Wegovy. The brands differ in approved use and maximum dose.

Semaglutide is a once-weekly GLP-1 receptor agonist sold under three brand names by Novo Nordisk: Ozempic and Rybelsus for type 2 diabetes, and Wegovy for chronic weight management. It mimics a gut hormone that signals satiety to the brain and slows gastric emptying. The injectable forms share the same molecule; only the approved indication and maximum dose differ.[2][3]

In the STEP-1 obesity trial, adults without diabetes taking Wegovy (semaglutide 2.4 mg) lost a mean of 14.9% of body weight at 68 weeks versus 2.4% with placebo. In the SELECT trial, semaglutide 2.4 mg reduced major adverse cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease but without diabetes.[1]

Bar chart of Semaglutide dose strengths on the FDA label: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, 2.4 mg, 7.2 mg (Wegovy HD)
Semaglutide comes in 6 strengths: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, 2.4 mg, 7.2 mg (Wegovy HD). The chart shows what the label lists. A prescriber sets the dose.[1]
At a glanceMultiple (brand-specific)
Active ingredient
semaglutide
Drug class
GLP-1 receptor agonist
Manufacturer
Novo Nordisk
FDA approved
December 2017 (Ozempic) · June 2021 (Wegovy)
Approved use
Type 2 diabetes (Ozempic/Rybelsus) · chronic weight management (Wegovy)
Off-label use
Use outside the approved brand/indication is off-label
Administration
Subcutaneous injection (weekly) · oral tablet (daily) · Once weekly (injectable)
Available doses
0.25 mg · 0.5 mg · 1 mg · 1.7 mg · 2.4 mg · 7.2 mg (Wegovy HD)
Half-life
≈ 7 days
Pregnancy
Discontinue ≥ 2 months before a planned pregnancy

Community health · CDC

Weight & metabolic health in Costa Mesa

Costa Mesa, California has a population of 111,918 people. The adult obesity rate in Costa Mesa is an age-adjusted estimate of 25.7%, 3.4 percentage points below the California state rate of 29.1%. Diagnosed diabetes reaches 9.5% of adults in Costa Mesa. Inactivity, meaning no leisure-time physical activity reported in the past month, affects 22.4% of adults in Costa Mesa.

of Costa Mesa adults have obesity
25.7%
diagnosed diabetes
9.5%
no regular physical activity
22.4%

Age-adjusted estimates for Costa Mesa, community figures, not individual risk. CDC PLACES, 2025 release.

Estimate your weight lossGLP-1s and fertility
§ 05Support around Semaglutide in Costa Mesa
6 fitness clubs

The prescription is one part. Here is the rest, in Costa Mesa.

Trials of semaglutide paired the drug with diet counseling and regular activity. Every name below is a real listing near Costa Mesa, CA, ordered as the registry lists them, never by who pays us.

Fitness clubs and recreation centers

Fitness clubs and recreation centers run classes and pools, an easier start than a weight room.

The 12 Fit Club - South Coast Metro
FITNESS
4.9 on Google · 177 reviews
3188 Airway Ave Ste H
Website
Trim Fitness Studio
FITNESS
4.8 on Google · 125 reviews
2937 Bristol St a200
Website
Self Made Training Facility Costa Mesa | Personal Fitness Center
FITNESS
4.9 on Google · 94 reviews
740 W 16th St
Society OC
FITNESS
5.0 on Google · 57 reviews
850 W 18th St Ste B
Website
24 Hour Fitness
GYM
4.3 on Google · 1,116 reviews
589 Anton Blvd
Website
Planet Fitness
GYM
4.0 on Google · 693 reviews
2200 Harbor Blvd
Website

Registered dietitians

A registered dietitian builds the food plan around your prescription. Call to ask about GLP-1 nutrition plans and insurance.

Gabriela Arce
RD
Registered dietitian
710 Joann St Apt B
Call 562-939-4579NPI 1699698043
Megan Barahona, RDN
RD
Registered dietitian
416 Enclave Cir Apt 205
Call 801-875-1683NPI 1346754397
Katherine Bennett, RD MPH CLEC
RD
Registered dietitian
2152 Elden Ave Apt 6
Call 949-838-7188NPI 1245787605
Dalia Beydoun, RD
RD
Registered dietitian
3100 Airway Ave Ste 139
Call 949-409-5676NPI 1356954283
Lillian Bodane, RD
RD
Registered dietitian
11301 Wilshire Blvd
Call 630-251-9296NPI 1922598465
Bonnie Burt, RD
RD
Registered dietitian
1000 S Coast Dr Apt E104
Call 562-745-7920NPI 1316213036
§ 06Clinical evidence
STEP 1 to 4 + SELECT (N = 17,604)

What the trials actually showed.

We summarize the STEP weight-management program, the SUSTAIN diabetes program, and the SELECT cardiovascular outcomes trial. Figures are means at each trial's primary endpoint.

STEP-1 randomized 1,961 adults with overweight or obesity (without diabetes) to semaglutide 2.4 mg or placebo for 68 weeks. Mean weight change was −14.9% with semaglutide versus −2.4% with placebo; 86% of treated patients lost ≥5% of body weight.[2]
STEP / SELECT endpoint table2.4 mg / 68 wk
Mean weight change (Wegovy 2.4 mg)
−14.9%
STEP-1, 68 wk vs −2.4% placebo[2]
Patients losing ≥5% body weight
86%
STEP-1, 2.4 mg[2]
Major adverse cardiac events
−20%
SELECT, HR 0.80[3]
HbA1c reduction (T2D)
−1.4 to −1.8%
SUSTAIN program[4]
Effect size varies with baseline characteristics and adherence. Individual response may differ materially.
average semaglutide weight loss →mapped to your starting weight
§ 07Safety & adverse events
from FDA label, sect. 6.1

Most Semaglutide side effects are stomach and gut effects.

In Wegovy's weight trials at 2.4 mg, the most common side effects were nausea (44%), diarrhea (30%), vomiting (24%), and constipation (24%). Ozempic's lower diabetes doses showed lower rates.[1] Serious events were rare but include pancreatitis, gallbladder disease, and an FDA boxed warning regarding thyroid C-cell tumors based on rodent data.[1]

Boxed warning. Boxed warning: risk of thyroid C-cell tumors. Contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN-2).
Effect
Frequency
Severity
Note
Nausea
15.8 to 44%
mild
Lowest on Ozempic 0.5 mg, highest on Wegovy 2.4 mg
Diarrhea
8.5 to 30%
mild
More frequent during dose escalation
Vomiting
5 to 24%
mild
Reduced by slower titration
Constipation
3.1 to 24%
mild
Abdominal pain
5.7 to 20%
moderate
Pancreatitis
<0.3%
serious
Discontinue if acute pancreatitis is suspected
Gallbladder disease
0.4 to 2.5%
serious
Gallstones. Lowest on Ozempic 1 mg, highest on Wegovy tablets. Risk rises with rapid weight loss
Thyroid C-cell tumors
rodent data
boxed warning
Contraindicated with MTC or MEN-2 history
§ 08Cost & coverage, published, not gated
USD · monthly

What Semaglutide costs, by how you pay.

The price you pay depends on your insurance plan, your diagnosis, and how you buy. Manufacturer self-pay programs cost far less than pharmacy retail. Here are the ranges.

Data sources: GoodRx national retail survey[6], CMS Part D formulary files[5], Novo Nordisk self-pay and savings pages.

Self-pay and savings card prices checked . Retail averages from May 2026.

Semaglutide monthly cost by how you pay
Wegovy, pharmacy retail$1,610 to $1,788per monthBrand-name retail average, May 2026[6]
Wegovy, NovoCare self-pay$349 to $399per monthPen $349, Wegovy HD 7.2 mg $399. Pill $149 to $299
Ozempic, pharmacy retail$1,476per monthBrand-name retail average, May 2026[6]
Commercial insurance (T2D)$25 to $250per month copayUsually covered for diabetes with prior authorization
Commercial insurance (weight)Often deniedWegovy is on-label but frequently requires PA and is denied
Medicare Part D$0 to $100per monthType 2 diabetes covered. Wegovy for weight management is $50 a month through the Medicare GLP-1 Bridge, Jul 2026 to Dec 2027[5]
Manufacturer savings cardas low as $25per monthOzempic and Wegovy cards, commercial insurance only, up to $100 a month in savings
Find Semaglutide providers in Costa Mesa

Physicians from the federal NPI registry. Ask each office whether it prescribes Semaglutide.

Semaglutide in other states

Physicians from the federal NPI registry in the states we cover. Ask each office whether it prescribes Semaglutide.

Related GLP-1 research
§ 09Frequently asked: Semaglutide in California

The questions people ask before they book.

Answers reviewed by the glp·helper Medical Team. Citations link to primary sources, never marketing copy.

Semaglutide is the active ingredient in three Novo Nordisk brands: Ozempic, Wegovy, and Rybelsus. No generic semaglutide is FDA-approved in the US. Ozempic and Rybelsus are approved for type 2 diabetes; Wegovy is approved for chronic weight management at a higher maximum dose (7.2 mg/week, Wegovy HD). Insurers treat the brands as separate drugs.[1]