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Dual GIP / GLP-1 receptor agonistFDA-approved May 2022 (Mounjaro) · November 2023 (Zepbound)Rx · Subcutaneous injection · Once weekly

Tirzepatide
(Mounjaro, Zepbound) in Independence, MO

Dr. Fahad Akhtar, M.D.
Medically reviewed by Dr. Fahad Akhtar, M.D.
Physician at g1v.me, an affiliated practice

Physicians near Independence, MO from the federal NPI registry. Ask each office whether it prescribes Mounjaro or Zepbound.[9]

  • Mounjaro: FDA-approved for type 2 diabetes.
  • Zepbound: FDA-approved for chronic weight management, and obstructive sleep apnea with obesity.
city providers
28
as of today

Same molecule (tirzepatide): Mounjaro in Independence, Zepbound in Independence

Other GLP-1 medicines: Ozempic in Independence, Wegovy in Independence, Semaglutide in Independence

§ 02Provider directory: Missouri
28 of 28 shown

Find a physician in Independence.

Every entry comes from the federal NPI registry. Ask each office what it prescribes. We do not accept payment for placement.

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Tirzepatide by Missouri town, physicians per town
§ 03Getting Tirzepatide in Independence
28 providers · Independence, MO

How to get Tirzepatide in Independence.

28 GLP-1 prescribers and 6 local resource types are on record for Independence, plus 3 nearby towns in the directory.

Physicians in Independence
28 physicians
28 physicians from the federal NPI registry in Independence, most listed as Family Medicine (15), Internal Medicine (11) and Internal Medicine, Endocrinology, Diabetes & Metabolism (2). A licensed clinician who evaluates you decides whether an FDA-approved GLP-1 fits. Telehealth rules vary by state. The nearest towns on record are Blue Springs (25 providers), Raytown (8 providers) and Kansas City (38 providers).
Around the prescription in Independence
6 listed nearby
8 dietitians, 6 gyms, 6 fitness clubs, 6 trainers, 6 physiotherapists and 5 places to move are on record near Independence.
Medicaid (weight loss)
Covered
As of April 2026, Missouri Medicaid covers GLP-1s for weight loss, usually with prior authorization and BMI criteria, on top of the standard diabetes coverage. Employer and private plans vary; coverage is a plan-design choice, not a state rule.

Medicaid status above is for weight-loss use and was compiled April 2026 from KFF and public Medicaid trackers; only 13 states cover it and several are mid-change, so confirm Missouri’s current Medicaid and plan rules before booking. GLPHelper provides information and provider matching, not medical or coverage advice.

§ 04Medication factsheet
cited · last review 2026.05.19

The molecule in Mounjaro and Zepbound. It acts on two gut-hormone pathways, GIP and GLP-1.

Tirzepatide is a once-weekly injection sold by Eli Lilly as Mounjaro (for type 2 diabetes) and Zepbound (for chronic weight management). It is the first approved dual GIP/GLP-1 receptor agonist. It activates two gut-hormone pathways rather than one, which is associated with greater average weight loss than single GLP-1 agonists.[2][3]

In SURMOUNT-1, adults with obesity (without diabetes) lost a mean of 20.9% of body weight on the 15 mg dose at 72 weeks, versus 3.1% on placebo. In the SURPASS-2 head-to-head diabetes trial, tirzepatide produced larger HbA1c and weight reductions than semaglutide 1 mg.[1]

Bar chart of Tirzepatide dose strengths on the FDA label: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg
Tirzepatide comes in 6 strengths: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg. The chart shows what the label lists. A prescriber sets the dose.[1]
At a glanceMultiple (brand-specific)
Active ingredient
tirzepatide
Drug class
Dual GIP / GLP-1 receptor agonist
Manufacturer
Eli Lilly
FDA approved
May 2022 (Mounjaro) · November 2023 (Zepbound)
Approved use
Type 2 diabetes (Mounjaro) · chronic weight management (Zepbound)
Off-label use
Use outside the approved brand/indication is off-label
Administration
Subcutaneous injection · Once weekly
Available doses
2.5 mg · 5 mg · 7.5 mg · 10 mg · 12.5 mg · 15 mg
Half-life
≈ 5 days
Pregnancy
Discontinue ≥ 2 months before a planned pregnancy; may reduce oral contraceptive efficacy

Community health · CDC

Weight & metabolic health in Independence

Independence, Missouri has a population of 123,011 people. The adult obesity rate in Independence is an age-adjusted estimate of 37.6%, 3 percentage points above the Missouri state rate of 34.6%. Diagnosed diabetes reaches 11% of adults in Independence. Inactivity, meaning no leisure-time physical activity reported in the past month, affects 32.6% of adults in Independence.

of Independence adults have obesity
37.6%
diagnosed diabetes
11%
no regular physical activity
32.6%

Age-adjusted estimates for Independence, community figures, not individual risk. CDC PLACES, 2025 release.

Estimate your weight losshow tirzepatide titration works
§ 05Support around Tirzepatide in Independence
6 gyms

The prescription is one part. Here is the rest, in Independence.

Trials of tirzepatide paired the drug with diet counseling and regular activity. Every name below is a real listing near Independence, MO, ordered as the registry lists them, never by who pays us.

Gyms near you

A gym gives you the regular movement that keeps muscle while the weight comes off.

Planet Fitness
GYM
4.5 on Google · 1,234 reviews
4545 B S Noland Rd
Website
Genesis Health Clubs - Lee's Summit
GYM
4.4 on Google · 958 reviews
900 NE Deerbrook St
Website
Total Body Fitness
GYM
4.5 on Google · 118 reviews
3680 NE Akin Dr #122
Website
9Round Kickboxing Fitness
GYM
4.8 on Google · 76 reviews
19321 E US Hwy 40 K
Website
Anytime Fitness
GYM
4.3 on Google · 69 reviews
15904 East 23rd St S
Website
The Bunker Gym KC
GYM
5.0 on Google · 23 reviews
14330 E 42nd St S
Website

Fitness clubs and recreation centers

Fitness clubs and recreation centers run classes and pools, an easier start than a weight room.

Beyond Fitness, LLC
FITNESS
5.0 on Google · 61 reviews
1102 NW Casey Blvd Ste F
Website
Life Adapted Fitness - Lee's Summit North
FITNESS
5.0 on Google · 33 reviews
631 NE Woods Chapel Rd
Website
Planet Fitness
GYM
4.5 on Google · 1,234 reviews
4545 B S Noland Rd
Website
Active Strength Co.
TRAINING
5.0 on Google · 168 reviews
1100 SE Century Dr
Website
9Round Kickboxing Fitness
GYM
4.8 on Google · 76 reviews
19321 E US Hwy 40 K
Website
Anytime Fitness
GYM
4.3 on Google · 69 reviews
15904 East 23rd St S
Website
§ 06Clinical evidence
STEP 1 to 4 + SELECT (N = 17,604)

What the trials actually showed.

We summarize the SURMOUNT weight-management program and the SURPASS diabetes program, including the SURPASS-2 head-to-head against semaglutide. Figures are means at each trial's primary endpoint.

SURMOUNT-1 randomized 2,539 adults with obesity (without diabetes) across 72 weeks. Mean weight change was −15.0% (5 mg), −19.5% (10 mg), and −20.9% (15 mg) versus −3.1% with placebo. A majority of patients on the higher doses lost ≥20% of body weight.[2]
STEP / SELECT endpoint table2.4 mg / 68 wk
Mean weight change (15 mg)
−20.9%
SURMOUNT-1, 72 wk vs −3.1% placebo[2]
Mean weight change (5 mg)
−15.0%
SURMOUNT-1, 72 wk[2]
HbA1c reduction (T2D)
−1.8 to −2.6%
SURPASS program[4]
vs. semaglutide 1 mg
Superior
SURPASS-2, HbA1c + weight[3]
Effect size varies with baseline characteristics and adherence. Individual response may differ materially.
average tirzepatide weight loss →mapped to your starting weight
§ 07Safety & adverse events
from FDA label, sect. 6.1

Most Tirzepatide side effects are stomach and gut effects.

In Zepbound's weight trials at 5 to 15 mg, the most common side effects were nausea (25 to 29%), diarrhea (19 to 23%), constipation (11 to 17%), and vomiting (8 to 13%). Mounjaro's diabetes trials showed lower rates at the same doses.[1] Serious events were rare but include pancreatitis, gallbladder disease, and an FDA boxed warning regarding thyroid C-cell tumors based on rodent data.[1]

Boxed warning. Boxed warning: risk of thyroid C-cell tumors. Contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN-2).
Effect
Frequency
Severity
Note
Nausea
12 to 29%
mild
Lowest on Mounjaro 5 mg, highest on Zepbound 10 mg
Diarrhea
12 to 23%
mild
More frequent during dose escalation
Vomiting
5 to 13%
mild
Reduced by slower titration
Constipation
6 to 17%
mild
Decreased appetite
5 to 11%
mild
Reported in Mounjaro's diabetes trials
Pancreatitis
<0.3%
serious
Discontinue if acute pancreatitis is suspected
Gallbladder disease
~1 to 2%
serious
Cholelithiasis risk rises with rapid weight loss
Thyroid C-cell tumors
rodent data
boxed warning
Contraindicated with MTC or MEN-2 history
§ 08Cost & coverage, published, not gated
USD · monthly

What Tirzepatide costs, by how you pay.

The price you pay depends on your insurance plan, your diagnosis, and how you buy. Manufacturer self-pay programs cost far less than pharmacy retail. Here are the ranges.

Data sources: GoodRx national retail survey[6], CMS Part D formulary files[5], Eli Lilly self-pay and savings pages.

Self-pay and savings card prices checked . Retail averages from May 2026.

Tirzepatide monthly cost by how you pay
Zepbound, pharmacy retail$1,000 to $1,300per monthBrand-name retail average, May 2026[6]
Zepbound, LillyDirect self-pay$299 to $699per monthKwikPen by dose: 2.5 mg $299, 5 mg $399, 7.5 mg $499, 10 to 15 mg $699. The $449 offer on 7.5 to 15 mg applies to the first purchase and to refills within 45 days. Vials start at $299
Mounjaro, pharmacy retail$1,000 to $1,200per monthBrand-name retail average, May 2026[6]
Commercial insurance (T2D)$25 to $250per month copayUsually covered for diabetes with prior authorization
Commercial insurance (weight)Often deniedZepbound is on-label but frequently requires PA
Medicare Part D$0 to $100per monthType 2 diabetes covered. Zepbound KwikPen for weight management is $50 a month through the Medicare GLP-1 Bridge, Jul 2026 to Dec 2027[5]
Manufacturer savings cardas low as $25per monthCommercial insurance only; eligibility limits apply
Find Tirzepatide providers in Independence

Physicians from the federal NPI registry. Ask each office whether it prescribes Tirzepatide.

Tirzepatide in other states

Physicians from the federal NPI registry in the states we cover. Ask each office whether it prescribes Tirzepatide.

Related GLP-1 research
§ 09Frequently asked: Tirzepatide in Missouri

The questions people ask before they book.

Answers reviewed by the glp·helper Medical Team. Citations link to primary sources, never marketing copy.

Tirzepatide is the active ingredient in two Eli Lilly brands: Mounjaro and Zepbound. No generic tirzepatide is FDA-approved in the US. Mounjaro is approved for type 2 diabetes; Zepbound is approved for chronic weight management. They share an active ingredient but carry different approved indications, and insurers treat them as separate products.[1]