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Dual GIP / GLP-1 receptor agonistFDA-approved May 2022 (Mounjaro) · November 2023 (Zepbound)Rx · Subcutaneous injection · Once weekly

Tirzepatide® providers &
prescriptions in Columbia, SC

Verified Tirzepatide providers in Columbia, SC. Checked against the NPI registry, sorted by waitlist, not by who pays us.[7]

city providers
36
as of today
median wait
8d
first visit
telehealth
71%
of providers
cash range
$25 to $1,150
monthly
§ 02Provider directory: South Carolina
36 of 36 shown

Find a Tirzepatide provider in South Carolina.

Every entry is checked against the NPI registry and the South Carolina medical board. Listings are ordered by current waitlist. The provider who can see you fastest appears first. We do not accept payment for placement.

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Browse by South Carolina city · /tirzepatide/south-carolina/{city}
§ 03Getting Tirzepatide in Columbia
36 providers · Columbia, SC

How to get Tirzepatide in Columbia.

36 GLP-1 prescribers and 7 local resource types are on record for Columbia, plus 2 nearby towns in the directory.

Prescribers in Columbia
36 prescribers
36 GLP-1 prescribers in Columbia, most listed as Internal Medicine, Endocrinology, Diabetes & Metabolism (11), Internal Medicine (10) and Family Medicine (10). Any South Carolina-licensed physician, nurse practitioner, or PA can prescribe Tirzepatide, over video or in person. The nearest towns on record are Charleston (37 providers) and Greenville (33 providers).
Around the prescription in Columbia
7 listed nearby
6 dietitians, 3 nutritionists, 6 gyms, 6 fitness clubs, 6 trainers, 6 physiotherapists and 6 places to move are on record near Columbia.
Medicaid (weight loss)
Diabetes only
As of April 2026, South Carolina Medicaid covers GLP-1s for diabetes but not for weight loss. Employer and private plans can still cover them; that is a plan-design choice, not a state rule.

Medicaid status above is for weight-loss use and was compiled April 2026 from KFF and public Medicaid trackers; only 13 states cover it and several are mid-change, so confirm South Carolina’s current Medicaid and plan rules before booking. GLPHelper provides information and provider matching, not medical or coverage advice.

§ 04Medication factsheet
cited · last review 2026.05.19

The molecule in Mounjaro and Zepbound. It acts on two gut-hormone pathways, GIP and GLP-1.

Tirzepatide is a once-weekly injection sold by Eli Lilly as Mounjaro (for type 2 diabetes) and Zepbound (for chronic weight management). It is the first approved dual GIP/GLP-1 receptor agonist. It activates two gut-hormone pathways rather than one, which is associated with greater average weight loss than single GLP-1 agonists.[2][3]

In SURMOUNT-1, adults with obesity (without diabetes) lost a mean of 20.9% of body weight on the 15 mg dose at 72 weeks, versus 3.1% on placebo. In the SURPASS-2 head-to-head diabetes trial, tirzepatide produced larger HbA1c and weight reductions than semaglutide 1 mg.[1]

At a glanceMultiple (brand-specific)
Generic name
tirzepatide
Drug class
Dual GIP / GLP-1 receptor agonist
Manufacturer
Eli Lilly
FDA approved
May 2022 (Mounjaro) · November 2023 (Zepbound)
Approved use
Type 2 diabetes (Mounjaro) · chronic weight management (Zepbound)
Off-label use
Use outside the approved brand/indication is off-label
Administration
Subcutaneous injection · Once weekly
Available doses
2.5 mg · 5 mg · 7.5 mg · 10 mg · 12.5 mg · 15 mg
Half-life
≈ 5 days
Pregnancy
Discontinue ≥ 2 months before a planned pregnancy; may reduce oral contraceptive efficacy

Community health · CDC

Weight & metabolic health in South Carolina

Diagnosed diabetes reaches 12.7% of adults in South Carolina.

of South Carolina adults have obesity
34.6%
diagnosed diabetes
12.7%

Age-adjusted estimates for South Carolina, community figures, not individual risk. CDC BRFSS 2024.

Estimate your weight lossGLP-1s and hair loss
§ 05Support around Tirzepatide in Columbia
6 fitness clubs

The prescription is one part. Here is the rest, in Columbia.

Trials of tirzepatide paired the drug with diet counseling and regular activity. Every name below is a real listing near Columbia, SC, ordered as the registry lists them, never by who pays us.

Fitness clubs and recreation centers

Fitness clubs and recreation centers run classes and pools, an easier start than a weight room.

Weston Lake
REC CENTER
4.5 on Google · 437 reviews
4420 Leesburg Rd
Website
MWR Central at the Robert B Solomon Activity Center
REC CENTER
4.6 on Google · 393 reviews
6510 Strom Thurmond Blvd
Website
Richland County Adult Activity Center
REC CENTER
4.6 on Google · 148 reviews
7494 Parklane Rd
Website
Richland County Recreation Commission
REC CENTER
4.6 on Google · 135 reviews
8614 Garners Ferry Rd
Website
Level Fitness Studio
FITNESS
4.9 on Google · 91 reviews
1514 Brentwood Dr Ste 101
Website
Jamie Scott Fitness
FITNESS
4.9 on Google · 66 reviews
702 Cross Hill Rd Ste 300-B
Website

Registered dietitians

A registered dietitian builds the food plan around your prescription. Call to ask about GLP-1 nutrition plans and insurance.

Lisa Akly, RD, LD
RD
Registered dietitian
9 Medical Park Ste 600
Call 803-296-2548NPI 1922258300
Joleen Alfalahi, RD. LD
RD
Registered dietitian
5 Richland Medical Park Dr
Call 803-296-2548NPI 1043646664
Phyllis Allen
RD
Registered dietitian
4010 N Main St
Call 803-786-0559NPI 1861830101
Kara Andrews, RDN
RD
Registered dietitian
4500 8Th Division Rd
Call 803-751-2160NPI 1861266009
Courtney Armstrong
RD
Registered dietitian
3020 Devine St
Call 803-814-5392NPI 1184042954
Jennifer Benedetto, RD
RD
Registered dietitian
6439 Garners Ferry Rd Rm 2A107
Call 803-580-4231NPI 1881377620
§ 06Clinical evidence
STEP 1 to 4 + SELECT (N = 17,604)

What the trials actually showed.

We summarize the SURMOUNT weight-management program and the SURPASS diabetes program, including the SURPASS-2 head-to-head against semaglutide. Figures are means at each trial's primary endpoint.

SURMOUNT-1 randomized 2,539 adults with obesity (without diabetes) across 72 weeks. Mean weight change was −15.0% (5 mg), −19.5% (10 mg), and −20.9% (15 mg) versus −3.1% with placebo. A majority of patients on the higher doses lost ≥20% of body weight.[2]
STEP / SELECT endpoint table2.4 mg / 68 wk
Mean weight change (15 mg)
−20.9%
SURMOUNT-1, 72 wk vs −3.1% placebo[2]
Mean weight change (5 mg)
−15.0%
SURMOUNT-1, 72 wk[2]
HbA1c reduction (T2D)
−1.8 to −2.6%
SURPASS program[4]
vs. semaglutide 1 mg
Superior
SURPASS-2, HbA1c + weight[3]
Effect size varies with baseline characteristics and adherence. Individual response may differ materially.
average tirzepatide weight loss →mapped to your starting weight
§ 07Safety & adverse events
from FDA label, sect. 6.1

Most side effects are gastrointestinal and resolve within weeks.

The most common adverse events in STEP trials were nausea (44%), diarrhea (30%), and vomiting (24%), more frequent at the 2.4 mg dose than at Ozempic doses, but typically transient.[1] Serious events were rare but include pancreatitis, gallbladder disease, and an FDA boxed warning regarding thyroid C-cell tumors based on rodent data.[8]

Boxed warning. Boxed warning: risk of thyroid C-cell tumors. Contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN-2).
Effect
Frequency
Severity
Note
Nausea
12 to 24%
mild
Dose-dependent; usually eases after titration
Diarrhea
12 to 19%
mild
More frequent during dose escalation
Vomiting
5 to 13%
mild
Reduced by slower titration
Constipation
6 to 17%
mild
Decreased appetite
5 to 11%
mild
Expected pharmacologic effect
Pancreatitis
<0.3%
serious
Discontinue if acute pancreatitis is suspected
Gallbladder disease
~1 to 2%
serious
Cholelithiasis risk rises with rapid weight loss
Thyroid C-cell tumors
rodent data
boxed warning
Contraindicated with MTC or MEN-2 history
§ 08Cost & coverage, published, not gated
USD · monthly

Most directories hide the price. We don't.

Cash prices vary roughly 50× between the brand-name retail rate and a manufacturer savings card. The number you actually pay depends on your insurance plan, your diagnosis code, and which pharmacy fills the script. Here are the ranges, plainly.

Data sources: GoodRx national retail survey[6], CMS Part D formulary files[5], Novo Nordisk patient access program.

Cash, Zepbound (no insurance)
$1,000 to $1,300
per month
Brand-name retail; Lilly self-pay vials lower for some doses[6]
Cash, Mounjaro (no insurance)
$1,000 to $1,200
per month
Brand-name retail average[6]
Commercial insurance (T2D)
$25 to $250
per month copay
Usually covered for diabetes with prior authorization
Commercial insurance (weight)
Often denied
Zepbound is on-label but frequently requires PA
Medicare Part D
$0 to $100
per month
T2D covered; weight-loss indication not covered by law[5]
Manufacturer savings card
as low as $25
per month
Commercial insurance only; eligibility limits apply
Updated weekly · last fetch 2026-05-18 04:00 UTCCost methodology →
Find Tirzepatide providers in South Carolina

NPI-verified Tirzepatide (tirzepatide) prescribers and clinics, ordered by availability, never by who pays us.

Tirzepatide in other states

Find NPI-verified Tirzepatide (tirzepatide) doctors, clinics, and pharmacies in the states we cover, ordered by availability, never by who pays us.

Related GLP-1 research
§ 09Frequently asked: Tirzepatide in South Carolina

The questions people ask before they book.

Answers reviewed by the GLPHelper Medical Team. Citations link to primary sources, never marketing copy.

Yes. Tirzepatide is the active molecule in both Eli Lilly products. Mounjaro is approved for type 2 diabetes; Zepbound is approved for chronic weight management. They are the same drug with different approved indications, and insurers treat them as separate products.[1]