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GLP-1 receptor agonistFDA-approved June 2021Rx · Subcutaneous injection · Once weekly

Wegovy® providers &
prescriptions in Tupelo, MS

Verified Wegovy providers in Tupelo, MS. Checked against the NPI registry, never ranked by who pays us.[7]

average Wegovy weight loss →trial-anchored estimate
city providers
30
as of today
§ 02Provider directory: Mississippi
30 of 30 shown

Find an Wegovy provider in Mississippi.

Every entry is checked against the federal NPI registry. We do not accept payment for placement.

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§ 03Getting Wegovy in Tupelo
30 providers · Tupelo, MS

How to get Wegovy in Tupelo.

30 GLP-1 prescribers and 6 local resource types are on record for Tupelo, plus 3 nearby towns in the directory.

Prescribers in Tupelo
30 prescribers
30 GLP-1 prescribers in Tupelo, most listed as Family Medicine (13), Internal Medicine (10) and Internal Medicine, Endocrinology, Diabetes & Metabolism (5). Any Mississippi-licensed physician, nurse practitioner, or PA can prescribe Wegovy, over video or in person. The nearest towns on record are Southaven (34 providers), Meridian (30 providers) and Jackson (38 providers).
Around the prescription in Tupelo
6 listed nearby
14 dietitians, 1 nutritionists, 6 gyms, 6 fitness clubs, 3 trainers and 6 physiotherapists are on record near Tupelo.
Medicaid (weight loss)
Covered
As of April 2026, Mississippi Medicaid covers GLP-1s for weight loss, usually with prior authorization and BMI criteria, on top of the standard diabetes coverage. Employer and private plans vary; coverage is a plan-design choice, not a state rule.

Medicaid status above is for weight-loss use and was compiled April 2026 from KFF and public Medicaid trackers; only 13 states cover it and several are mid-change, so confirm Mississippi’s current Medicaid and plan rules before booking. GLPHelper provides information and provider matching, not medical or coverage advice.

§ 04Medication factsheet
cited · last review 2026.05.19

An injectable medication for chronic weight management in adults. Same molecule as Ozempic, higher dose.

Wegovy is the brand name for semaglutide at the higher 2.4 mg dose. It is the same molecule as Ozempic, marketed by the same manufacturer for a different FDA-approved indication. It is a once-weekly subcutaneous injection in the GLP-1 receptor agonist class.[2][3]

In the STEP-1 randomized trial, 68 weeks of weekly 2.4 mg semaglutide produced a mean body-weight reduction of 14.9%, roughly 2.5× the weight loss seen at the Ozempic 1 mg dose. Wegovy is FDA-approved for chronic weight management in adults with a BMI ≥ 30, or ≥ 27 with at least one weight-related comorbidity such as hypertension or dyslipidemia.[1]

At a glanceNDC 0169-4525
Generic name
semaglutide
Drug class
GLP-1 receptor agonist
Manufacturer
Novo Nordisk
FDA approved
June 2021
Approved use
Chronic weight management in adults with obesity or overweight with weight-related comorbidities
Off-label use
Off-label use is uncommon. Ozempic is the FDA-approved formulation for type 2 diabetes
Administration
Subcutaneous injection · Once weekly
Available doses
0.25 mg · 0.5 mg · 1 mg · 1.7 mg · 2.4 mg
Half-life
≈ 7 days
Pregnancy
Discontinue ≥ 2 months before planned pregnancy

Community health · CDC

Weight & metabolic health in Tupelo

Tupelo, Mississippi has a population of 37,923 people. The adult obesity rate in Tupelo is an age-adjusted estimate of 36.3%, 4.1 percentage points below the Mississippi state rate of 40.4%. Diagnosed diabetes reaches 12.4% of adults in Tupelo. Inactivity, meaning no leisure-time physical activity reported in the past month, affects 30.7% of adults in Tupelo.

of Tupelo adults have obesity
36.3%
diagnosed diabetes
12.4%
no regular physical activity
30.7%

Age-adjusted estimates for Tupelo, community figures, not individual risk. CDC PLACES, 2025 release.

Estimate your weight lossOzempic babies explained
§ 05Support around Wegovy in Tupelo
6 gyms

The prescription is one part. Here is the rest, in Tupelo.

Trials of semaglutide paired the drug with diet counseling and regular activity. Every name below is a real listing near Tupelo, MS, ordered as the registry lists them, never by who pays us.

Gyms near you

A gym gives you the regular movement that keeps muscle while the weight comes off.

Planet Fitness
GYM
4.6 on Google · 567 reviews
1800 N Gloster St
Website
Mississippi Mecca
GYM
4.9 on Google · 92 reviews
248 S Green St
Website
Anytime Fitness
GYM
4.4 on Google · 84 reviews
2421 W Main St
Website
Peak Fitness Tupelo
GYM
4.9 on Google · 65 reviews
1491 Beech Springs Rd
Website
Premiere Lady
GYM
4.4 on Google · 43 reviews
1670 McClure Cove Ste a
Website
Snap Fitness Tupelo
GYM
4.8 on Google · 41 reviews
549 Coley Rd
Website

Fitness clubs and recreation centers

Fitness clubs and recreation centers run classes and pools, an easier start than a weight room.

North Mississippi Wellness Center-Tupelo
FITNESS
4.6 on Google · 154 reviews
1030 S Madison St
Website
ATC Fitness
FITNESS
4.3 on Google · 79 reviews
4360 Mall Dr
Website
UFM Fitness Kickboxing & Jiu-Jitsu
FITNESS
5.0 on Google · 54 reviews
1715 McCullough Blvd Ste A
Website
Selfish Fitness Studio
FITNESS
3.8 on Google · 6 reviews
1142 W Main St Ste C
Website
Planet Fitness
GYM
4.6 on Google · 567 reviews
1800 N Gloster St
Website
Mississippi Mecca
GYM
4.9 on Google · 92 reviews
248 S Green St
Website
§ 06Clinical evidence
STEP 1 to 4 + SELECT (N = 17,604)

What the trials actually showed.

We summarize results from the STEP program, the global Phase IIIa trials Novo Nordisk submitted to the FDA for the weight-management indication, and the SELECT cardiovascular outcomes trial. Numbers below are means at the 68-week endpoint, 2.4 mg weekly dose.

STEP-1 randomized 1,961 adults with obesity to weekly 2.4 mg semaglutide vs placebo over 68 weeks. Mean body-weight reduction was 14.9% on semaglutide vs 2.4% on placebo. 86.4% of patients on semaglutide achieved ≥ 5% weight loss vs 31.5% on placebo.[4]
STEP / SELECT endpoint table2.4 mg / 68 wk
Weight change
−14.9%
vs −2.4% placebo, 68 wk[4]
≥ 5% weight loss
86.4%
vs 31.5% placebo[4]
≥ 15% weight loss
50.5%
vs 4.9% placebo[4]
Major adverse cardiac events
−20%
HR 0.80 vs. placebo (SELECT)[2]
Effect size varies with baseline characteristics and adherence. Individual response may differ materially.
average Wegovy weight loss →mapped to your starting weight
§ 07Safety & adverse events
from FDA label, sect. 6.1

Most side effects are gastrointestinal and resolve within weeks.

The most common adverse events in STEP trials were nausea (44%), diarrhea (30%), and vomiting (24%), more frequent at the 2.4 mg dose than at Ozempic doses, but typically transient.[1] Serious events were rare but include pancreatitis, gallbladder disease, and an FDA boxed warning regarding thyroid C-cell tumors based on rodent data.[8]

Boxed warning. Contraindicated in personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN-2).
Effect
Frequency
Severity
Note
Nausea
44%
mild
More common than at Ozempic doses; usually transient and dose-dependent
Diarrhea
30%
mild
Most frequent during dose escalation phase
Vomiting
24%
mild
Slower titration reduces incidence
Constipation
24%
mild
Hydration + fiber recommended
Abdominal pain
20%
moderate
Pancreatitis
<0.3%
serious
Discontinue if confirmed; class warning
Gallbladder disease
1.6%
serious
Cholelithiasis risk elevated with rapid weight loss
Thyroid C-cell tumors
rodent data
boxed warning
Contraindicated in MTC or MEN-2 history
§ 08Cost & coverage, published, not gated
USD · monthly

Most directories hide the price. We don't.

Cash prices vary roughly 50× between the brand-name retail rate and a manufacturer savings card. The number you actually pay depends on your insurance plan, your diagnosis code, and which pharmacy fills the script. Here are the ranges, plainly.

Data sources: GoodRx national retail survey[6], CMS Part D formulary files[5], Novo Nordisk patient access program.

Cash (no insurance)
$1,300 to $1,500
per month
National pharmacy average, brand-name[6]
Commercial insurance (covered)
$25 to $400
per month copay
Varies by PBM; many plans require BMI ≥ 30 + step therapy
Commercial insurance (denied)
Typically denied
Most plans exclude weight-loss medications from formulary
Medicare Part D
Not covered
Statutory exclusion of weight-loss drugs in original Medicare[5]
Manufacturer savings card
as low as $0
per month for 12 mo
Commercial only; eligibility limits apply
Compounded semaglutide
$150 to $400
per month
503A pharmacies; FDA scrutiny ongoing[8]
Updated weekly · last fetch 2026-05-18 04:00 UTCCost methodology →
Find Wegovy providers in Mississippi

NPI-verified Wegovy (semaglutide) prescribers and clinics, never ranked by who pays us.

Wegovy in other states

Find NPI-verified Wegovy (semaglutide) doctors, clinics, and pharmacies in the states we cover, never ranked by who pays us.

Related GLP-1 research
§ 09Frequently asked: Wegovy in Mississippi

The questions people ask before they book.

Answers reviewed by the GLPHelper Medical Team. Citations link to primary sources, never marketing copy.

FDA approval is for adults with a BMI ≥ 30, or ≥ 27 with at least one weight-related comorbidity (hypertension, type 2 diabetes, dyslipidemia). Adolescents 12+ with a BMI in the 95th percentile or higher were added to the label in December 2022.[1]