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glphelper.com/zepbound/tennessee/knoxville
Dual GIP / GLP-1 receptor agonistFDA-approved November 2023Rx · Subcutaneous injection · Once weekly

Zepbound® providers &
prescriptions in Knoxville, TN

Dr. Fahad Akhtar, M.D.
Medically reviewed by Dr. Fahad Akhtar, M.D.
Physician at g1v.me, an affiliated practice

Physicians near Knoxville, TN from the federal NPI registry. Ask each office whether it prescribes Zepbound.[9]

average Zepbound weight loss →trial-anchored estimate
city providers
42
as of today

Same molecule (tirzepatide): Tirzepatide in Knoxville, Mounjaro in Knoxville

Other GLP-1 medicines: Ozempic in Knoxville, Wegovy in Knoxville, Semaglutide in Knoxville

§ 02Provider directory: Tennessee
42 of 42 shown

Find a Zepbound provider in Knoxville.

Every entry comes from the federal NPI registry. Ask each office what it prescribes. We do not accept payment for placement.

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Provider
City
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Zepbound by Tennessee town, physicians per town
§ 03Getting Zepbound in Knoxville
42 providers · Knoxville, TN

How to get Zepbound in Knoxville.

42 GLP-1 prescribers and 7 local resource types are on record for Knoxville, plus 3 nearby towns in the directory.

Physicians in Knoxville
42 physicians
42 physicians from the federal NPI registry in Knoxville, most listed as Internal Medicine, Endocrinology, Diabetes & Metabolism (15), Family Medicine (12) and Internal Medicine (11). A licensed clinician who evaluates you decides whether an FDA-approved GLP-1 fits. Telehealth rules vary by state. The nearest towns on record are Maryville (25 providers), Oak Ridge (26 providers) and Morristown (24 providers).
Around the prescription in Knoxville
7 listed nearby
6 dietitians, 5 nutritionists, 6 gyms, 6 fitness clubs, 6 trainers, 6 physiotherapists and 6 places to move are on record near Knoxville.
Medicaid (weight loss)
Covered
As of April 2026, Tennessee Medicaid covers GLP-1s for weight loss, usually with prior authorization and BMI criteria, on top of the standard diabetes coverage. Employer and private plans vary; coverage is a plan-design choice, not a state rule.

Medicaid status above is for weight-loss use and was compiled April 2026 from KFF and public Medicaid trackers; only 13 states cover it and several are mid-change, so confirm Tennessee’s current Medicaid and plan rules before booking. GLPHelper provides information and provider matching, not medical or coverage advice.

§ 04Medication factsheet
cited · last review 2026.05.19

An injectable medication for chronic weight management in adults. Same molecule as Mounjaro.

Zepbound is the brand name Eli Lilly uses for tirzepatide approved for chronic weight management. It is a once-weekly subcutaneous injection and the first approved dual GIP/GLP-1 receptor agonist. The identical molecule, marketed as Mounjaro, is the FDA-approved formulation for type 2 diabetes.[2][3]

In SURMOUNT-1, adults with obesity (without diabetes) lost a mean of 20.9% of body weight on the 15 mg dose at 72 weeks, versus 3.1% with placebo. That is among the largest average weight reductions reported for an anti-obesity medication. Zepbound is approved as an adjunct to a reduced-calorie diet and increased physical activity.[1]

Bar chart of Zepbound dose strengths on the FDA label: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg
Zepbound comes in 6 strengths: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg. The chart shows what the label lists. A prescriber sets the dose.[1]
At a glanceMultiple (per dose)
Active ingredient
tirzepatide
Drug class
Dual GIP / GLP-1 receptor agonist
Manufacturer
Eli Lilly
FDA approved
November 2023
Approved use
Chronic weight management (adults with obesity, or overweight with a weight-related condition) and moderate to severe obstructive sleep apnea in adults with obesity
Off-label use
Type 2 diabetes (Mounjaro is the FDA-approved tirzepatide for diabetes)
Administration
Subcutaneous injection · Once weekly
Available doses
2.5 mg · 5 mg · 7.5 mg · 10 mg · 12.5 mg · 15 mg
Half-life
≈ 5 days
Pregnancy
Discontinue ≥ 2 months before a planned pregnancy; may reduce oral contraceptive efficacy

Community health · CDC

Weight & metabolic health in Knoxville

Knoxville, Tennessee has a population of 190,740 people. The adult obesity rate in Knoxville is an age-adjusted estimate of 37.5%, 0.1 percentage points below the Tennessee state rate of 37.6%. Diagnosed diabetes reaches 13.2% of adults in Knoxville. Inactivity, meaning no leisure-time physical activity reported in the past month, affects 27.7% of adults in Knoxville.

of Knoxville adults have obesity
37.5%
diagnosed diabetes
13.2%
no regular physical activity
27.7%

Age-adjusted estimates for Knoxville, community figures, not individual risk. CDC PLACES, 2025 release.

Estimate your weight lossOzempic side effects in men
§ 05Support around Zepbound in Knoxville
5 nutritionists

The prescription is one part. Here is the rest, in Knoxville.

Trials of tirzepatide paired the drug with diet counseling and regular activity. Every name below is a real listing near Knoxville, TN, ordered as the registry lists them, never by who pays us.

Nutritionists

A nutritionist helps you get enough protein and fiber while the medication cuts your appetite. Call to ask what they cover.

Soonja Choo
NUTRITIONIST
Nutritionist · Education
137 E Blount Ave
Call 865-549-2121NPI 1497814362
Jaimie Georg
NUTRITIONIST
Nutritionist · Education
3469 New Highway 68
Call 423-442-5934NPI 1073004420
Laurielle Godoy-Canal
NUTRITIONIST
Nutritionist
5724 Sanford Rd
Call 865-264-0574NPI 1265350045
Danielle Puno, M.Ed., NC
NUTRITIONIST
Nutritionist · Education
1806 Williamson Ct Ste 120
Call 615-538-0755NPI 1114761772
Lisa Smallen-Lee
NUTRITIONIST
Nutritionist · Education
4335 Maynardville Hwy
Call 865-992-3867NPI 1952442618

Fitness clubs and recreation centers

Fitness clubs and recreation centers run classes and pools, an easier start than a weight room.

Navitat Knoxville
REC CENTER
4.9 on Google · 630 reviews
2915 Island Home Ave
Website
TRECS
REC CENTER
4.4 on Google · 229 reviews
2111 Volunteer Blvd
Website
Frankies Body Shop The Gym and Personal Training
FITNESS
4.7 on Google · 128 reviews
3541 N Broadway
Website
Crossfit Knoxville
FITNESS
4.9 on Google · 120 reviews
9311 Kingston Pike
Website
E V Davidson Recreation Center
REC CENTER
4.3 on Google · 118 reviews
3124 Wilson Ave
Website
Planet Fitness
FITNESS
4.1 on Google · 115 reviews
7530 Thunder Ln
Website
§ 06Clinical evidence
STEP 1 to 4 + SELECT (N = 17,604)

What the trials actually showed.

We summarize the SURMOUNT weight-management program. Figures are means at the 72-week primary endpoint, by dose.

SURMOUNT-1 randomized 2,539 adults with obesity (without diabetes) across 72 weeks. Mean weight change was −15.0% (5 mg), −19.5% (10 mg), and −20.9% (15 mg) versus −3.1% with placebo. A majority of patients on the higher doses lost ≥20% of body weight.[2]
STEP / SELECT endpoint table2.4 mg / 68 wk
Mean weight change (15 mg)
−20.9%
SURMOUNT-1, 72 wk vs −3.1% placebo[2]
Mean weight change (10 mg)
−19.5%
SURMOUNT-1, 72 wk[2]
Mean weight change (5 mg)
−15.0%
SURMOUNT-1, 72 wk[2]
Effect size varies with baseline characteristics and adherence. Individual response may differ materially.
average Zepbound weight loss →mapped to your starting weight
§ 07Safety & adverse events
from FDA label, sect. 6.1

Most Zepbound side effects are stomach and gut effects.

In Zepbound's weight trials at 5 to 15 mg, the most common side effects were nausea (25 to 29%), diarrhea (19 to 23%), constipation (11 to 17%), and vomiting (8 to 13%). Most reports came during dose escalation and decreased over time.[1] Serious events were rare but include pancreatitis, gallbladder disease, and an FDA boxed warning regarding thyroid C-cell tumors based on rodent data.[1]

Boxed warning. Boxed warning: risk of thyroid C-cell tumors. Contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN-2).
Effect
Frequency
Severity
Note
Nausea
25 to 29%
mild
Most reports came during dose escalation and decreased over time
Diarrhea
19 to 23%
mild
More frequent during dose escalation
Vomiting
8 to 13%
mild
Reduced by slower titration
Constipation
11 to 17%
mild
Abdominal pain
9 to 10%
moderate
Pancreatitis
<0.3%
serious
Discontinue if acute pancreatitis is suspected
Gallbladder disease
~1 to 2%
serious
Cholelithiasis risk rises with rapid weight loss
Thyroid C-cell tumors
rodent data
boxed warning
Contraindicated with MTC or MEN-2 history
§ 08Cost & coverage, published, not gated
USD · monthly

What Zepbound costs, by how you pay.

The price you pay depends on your insurance plan, your diagnosis, and how you buy. Manufacturer self-pay programs cost far less than pharmacy retail. Here are the ranges.

Data sources: GoodRx national retail survey[6], CMS Part D formulary files[5], Eli Lilly self-pay and savings pages.

Self-pay and savings card prices checked . Retail averages from May 2026.

Zepbound monthly cost by how you pay
Pharmacy retail (no insurance)$1,000 to $1,300per monthBrand-name retail average, May 2026[6]
LillyDirect self-pay, KwikPen or vial$299 to $699per monthKwikPen by dose: 2.5 mg $299, 5 mg $399, 7.5 mg $499, 10 to 15 mg $699. The $449 offer on 7.5 to 15 mg applies to the first purchase and to refills within 45 days. Vials start at $299
Commercial insurance (weight)Often deniedOn-label for obesity but frequently requires prior authorization
Medicare GLP-1 Bridge$50per monthKwikPen only, Jul 1, 2026 to Dec 31, 2027, Part D enrollees who meet weight and health criteria[5]
Manufacturer savings cardas low as $25per monthCommercial insurance with coverage only; eligibility limits apply
Find Zepbound providers in Knoxville

Physicians from the federal NPI registry. Ask each office whether it prescribes Zepbound.

Zepbound in other states

Physicians from the federal NPI registry in the states we cover. Ask each office whether it prescribes Zepbound.

Related GLP-1 research
§ 09Frequently asked: Zepbound in Tennessee

The questions people ask before they book.

Answers reviewed by the glp·helper Medical Team. Citations link to primary sources, never marketing copy.

Zepbound and Mounjaro are both tirzepatide, made by Eli Lilly, but they carry different FDA-approved indications. Zepbound is approved for chronic weight management; Mounjaro is approved for type 2 diabetes. Insurers treat them as separate products, and weight-loss coverage is far more restricted than diabetes coverage.[1]